Cell growth cycle block of T cell hybridomas upon activation with antigen.
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چکیده
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Cell growth cycle block of T cell hybridomas upon activation with antigen
Stimulation of antigen-specific T cell hybridomas with the appropriate antigen/MHC combination, at concentrations that resulted in the secretion of the lymphokine interleukin 2, resulted in a dose-dependent decrease in both [3H]thymidine incorporation and cell growth. Flow cytometric studies demonstrated that stimulation with antigen resulted in a cell cycle block that was most evident at the G...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1987
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.165.1.173